Chemo regimens with cycle calendars and toxicity — watches for the heart, myeloma, fevers and immunotherapy, and the oral chemotherapy diary.
Regimen templates written out drug by drug with the day of the cycle and the dose as the protocol states it, a cycle calendar generated from the regimen’s own spacing, and CTCAE toxicity graded 1 to 5 against the cycle it happened on. Watches on a running regimen: the heart on a cardiotoxic drug, echo by echo (LVEF, and GLS when measured) against the patient’s own first echo, flagged at the drop the treating doctor sets; myeloma markers between cycles (M-spike, kappa and lambda with their ratio, bone findings) and the doctor’s response category under the IMWG criteria; a fever on chemotherapy as an episode whose clock runs from presentation to the first antibiotic, against the unit’s own target with its source; and an immunotherapy side-effect screen at each visit — which organ systems were asked about, and any finding graded on CTCAE. IMWG and CTCAE are cited by name; no threshold ships. The oral chemotherapy diary: a course taken at home, written by the prescriber as prescribed (the schedule in their words, and only if they choose one, the rating to flag at); each dose taken, missed or held and each side-effect rated none, mild, moderate or severe as the patient reported it, by phone, at a visit or from their diary; a rating worse than that symptom’s last report, or at the prescriber’s level, is flagged to the team until a clinician reviews it — between clinic visits rather than at the next one. Nothing changes a dose or schedule.
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