Diabetes Stem Cell Treatment In India

Diabetes Stem Cell Treatment

What is Diabetes Type 2?

 

Diabetes is the disease affecting the metabolism of glucose to a great extent. The glucose is required by the cells for energy production and normal functioning. This glucose comes in the blood from the food we eat and carried to the cellular level by an important hormone known as the insulin. Once the meal is consumed by the body, it breaks down into the glucose and other nutrients which are then absorbed in the bloodstream from the gastrointestinal tract. This glucose is then transferred from the blood stream to the cells. The diabetes develops when the body either can’t prepare insulin or can’t respond to the insulin. Diabetes can be mainly differentiated into two broad categories such as Diabetes Type 1 & Diabetes Type 2.

Type 2 diabetes formerly called as non insulin dependent diabetes occurs as a result of body’s inability to utilize insulin. It is the most common form of diabetes accounting for more than 90 % of the diabetes cases.

HOW PREVALENT IS DIABETES TYPE 2?

By the end of 2013, estimated deaths due to diabetes were almost 2 million. The epidemiology survey has concluded that more than 80% of the deaths are from low and middle income countries. WHO has projected that diabetes can be the seventh leading cause of death globally by the end of 2020.

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More About Diabetes Stem Cell Treatment

Diabetes is a common chronic condition, having no definite cure, treatment is primarily focused on controlling the blood sugar levels by medicines, insulin injections and maintaining a proper diet. Diabetes can affect every organ of the body, so essential to keep sugar levels under control. With the use of stem cell therapy, there might be a cure for diabetes. An embryonic stem cell can develop a beta cell and these cells of the pancreas can be then transferred to diabetic patients.

Types of Diabetes

There are two major types of diabetes: type 1 and type 2.


Type 1 Diabetes: Insulin-dependent diabetes mellitus (IDDM), or juvenile onset diabetes mellitus-  here the beta cells of the pancreas, which are responsible for insulin production, are attacked by the immune system, and  thus incapable of making insulin. People with type 1 diabetes must rely on insulin medication for survival. 

Type 2 Diabetes: Non-insulin dependent diabetes mellitus (NIDDM), or adult onset diabetes mellitus (AODM). In type 2 diabetes, patients can produce insulin, but its inadequate for their body's needs, as there is a lack of sensitivity to insulin by the cells of the body. 

 


Symptoms of Diabetes

Weight loss 

Frequent Urination 

Thirsty 

Tiredness 

Blurry vision 

Wounds that won’t heal 

Numbness or tingling hands and feet 

Sexual problems

 


Tests and Diagnosis for Diabetes

HBA1C - Glycated hemoglobin (A1C) test. An A1C level of 6.5 percent or higher on two separate tests indicates that you have diabetes

Random blood sugar test

Fasting blood sugar test

Oral glucose tolerance test

Urine examination

 


Types of  Stem cell Transplant

Autologous Transplant: When the stem cells come from your own bloodor bone marrow, it is called an autologous transplant

Allogenic transplant: When the stem cells come from another person, itis called an allogeneic transplant. The donors immune system markers areclosely matched to the recipient. 

 


Procedure

Before Procedure

Before you have stem cell treatment, your physician will discuss the treatment modalities in detail. 

Evaluation-You will first be evaluated to find out if you are eligible for stem cell treatment.

Many different medical tests will be performed, these might include:

A complete health history and physical exam

Heart tests

Lung function tests, such as a chest x-ray and PFTs

Blood tests, such as a complete blood count, blood chemistry,

Hepatitis B, CMV, and HIV

Advised to stop all non-steroidal anti-inflammatory drugs (NSAIDs) one week prior the procedure

Asked to stop  any medication or supplements that thin the blood like aspirin

 


During Procedure 

Stem cells are normally extracted from the patients fat tissue or bone marrow.

The sample is centrifuged 

The stem cells are then implantedeither Intra arterial,  intravenous, Lumbar puncture, Intramuscular or Intradermal

Implantation is a painless process and no anesthesia required.

 


After Procedure

Patient generally monitored for about a day in the hospital.

More stable blood sugar levels and a gradual decrease of HbA1C

Normalized blood counts

50% decrease in insulin shot requirements 

Reduced severity and frequency of diabetes-related complications

Improved sexual capacity

Boosted immunity

Better overall life quality.

 


Complications

Stem cell injections come from a patient’s own body so the rejection risk is extremely low. Side effects from the infusion are rare and usually mild, they may be :


Infection, Fever 

 


Factors Affecting Cost of stem cell treatment 

The cost to the patient depends on a variety of factors like:


  1. The hospital, the patient chooses
  2. Fee for the team of doctors
  3. Cost of medications
  4. Cost for stem cell collection process, cost of the procedure 
  5. Number of stem cell infusions 
  6. Standard tests and diagnosis 
  7. Cost of the follow–up after the procedure